Part 2: Confirming an outbreak of enterovirus

Part 2: Confirming an outbreak of enterovirus D68 Local health authorities confirmed 13 similar cases were reported by three other Chicago area hospitals during the past week. Patients were male and female, ranging in age from six to 10 years. Two male patients, both aged seven years, died within a week of being admitted to PICU. The Illinois Department of Public Health requested CDC assistance. Local diagnostic laboratory testing using polymerase chain reaction assay on a multiplex platform was able to determine if enteroviruses or rhinoviruses were present but not tell which (i.e., specimens were reported positive for enterovirus/rhinovirus). Viral genome sequencing at CDC was able to give more specific results. The CDC found samples from all four patients from Hospital University of Chicago Medicine Center Children’s Hospital and 10 of 13 patients from the other area hospitals to be positive for EV-D68. CDC epidemiologists arrived the next day and teamed up with local health department epidemiologists and physicians from affected Chicago hospitals to investigate the outbreak. An epidemiologist and physician interviewed the parent of each patient. 2: What types of information should be collected during this investigation?

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