An older adult presents for evaluation of lower extremity pain.

Which statement provides accurate information about a key difference between seasonal influenza and pandemic influenza? Pandemic influenza has the potential to spread globally because of its highly infectious nature in humans. Seasonal influenza is caused by viral infections; pandemic influenza is more likely to be bacterial in nature. People over the age of 50 years who have chronic illness should be vaccinated yearly to decrease the risk for pandemic influenza. Humans have a natural resistance to viral infections found in animals and birds and do not require immunization against pandemic influenza.

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