A 48-year-old client, who has been prescribed estrogen and progestin hormone replacement therapy (HR

A 48-year-old client, who has been prescribed estrogen and progestin hormone replacement therapy (HRT) for menopausal symptoms, also has a history of major depressive disorder and is currently taking amitriptyline. The client reports a recent worsening of their depressive symptoms. Which intervention should the nurse prioritize in this scenario? Monitor the client’s depressive symptoms and consider adjusting the amitriptyline dosage if necessary. Initiate a switch to selective serotonin reuptake inhibitors (SSRIs) while discontinuing the amitriptyline. Advise the client to stop taking the amitriptyline immediately to reduce the risk of drug interactions with their HRT. Recommend discontinuing hormone replacement therapy to alleviate potential drug interactions with amitriptyline.

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