What is meant by the sickle cell

What is meant by the sickle cell trait? What is the genotype of an individual who has this trait? Describe the pathophysiology of sickle cell anemia. What precipitates sickling? What is meant by sickle cell “crisis”? Identify the potential complications of a sickling crisis. Explain why an individual with sickle cell anemia may experience the following signs and symptoms: Jaundice: Cerebrovascular accident: Frequent infections: Splenomegaly: Congestive heart failure: Is there any means of preventing sickle cell anemia? Define Polycythemia. Differentiate between primary and secondary polycythemia. Describe the signs and symptoms and complications of polycythemia. BLOOD CLOTTING List the warning signs of excessive bleeding. Describe the diagnostic tests that can be employed to identify and/or monitor bleeding disorders. Describe how and explain why each of the following factors would affect hemostasis Liver disease: Ingestion of aspirin: Prolonged antibiotic therapy: Administration of heparin: Vitamin K deficiency: Prolonged inactivity: Polycythemia: Thrombocytopenia Increased hematocrit: Administration of warfarin:

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