There has been a sudden increase in

There has been a sudden increase in watery diarrhea on a medical unit and Clostridioides difficile (C. difficile) is now suspected. As an Infection Preventionist (IP), you have been asked to advise the medical team about laboratory tests for C. difficile. Which of the following statements regarding laboratory testing for C. difficile is/are accurate? I. Polymerase chain reaction (PCR) tests approved by the Food and Drug Administration have high sensitivity and specificity for testing the presence of toxin-producing C. difficile organisms. II. Toxigenic culture results have been demonstrated to act as a gold-standard against other test modalities tested in clinical performance trials. III. Enzyme immunoassay (EIA) testing for C. difficile toxins A and B is rapid and more sensitive than both toxigenic culture and PCR, thus making it ideal for clinical diagnosis of C. difficile infection. IV. Antigen detection tests for C. difficile have a high specificity, allowing them to be used as stand-alone tests for detecting toxins. Use the link provided for this information: CDC FAQs for Clinicians about Links to an external site.C. diff, June 27, 2022Links to an external site. If for any reason this link does not work, search for: “Frequently Asked Questions for Clinicians about C. diff.” from the Centers for Disease Control & Prevention. Group of answer choices Statements I & IV Statements I &II Statements II, III, & IV Statements I, II, & II

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