APPENDIX F Appraisal Guide: Findings of a

APPENDIX F Appraisal Guide: Findings of a Quantitative Review Citation:Sujata, N., Tobin, R., Kaur, R., Aneja, A., Khanna, M., & Hanjoora, V. M. (2016). Randomized controlled trial of tranexamic acid among parturients at increased risk for postpartum hemorrhage undergoing cesarean delivery. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 133(3), 312-315. https://doi.org/10.1016/j.ijgo.2015.09.032 Synopsis What was the purpose of the study (research questions, purposes, and hypotheses)? The study aimed to assess tranexamic acid’s effects among patients undergoing cesarean delivery who were at high risk of postpartum hemorrhage. How was the sample obtained? What inclusion or exclusion criteria were used? Who from the sample actually participated or contributed data (demographic or clinical profile and dropout rate)? What methods were used to collect data (e.g., sequence, timing, types of data, and measures)? How was the sample size determined? Were patients randomly assigned to treatment groups? What are the main findings? Is the study published in a source that required peer review?  Yes   No   Not clear Was the design used appropriate to the research ?  Yes   No   Not clear *Did the data obtained and the analysis conducted answer the research ?  Yes   No   Not clear Were the measuring instruments reliable and valid?  Yes   No   Not clear *Were important extraneous variables and bias controlled?  Yes   No   Not clear *Was the study free of extraneous variables introduced by how, when, and wherethe study was done?  Yes   No   Not clear *If an intervention was tested, answer the following five questions: 1. Were participants randomly assigned togroups and werethe two groups similar at thestart (before the intervention)?  Yes   No   Not clear Were the interventions well defined and consistently delivered?  Yes   No   Not clear Were the groups treated equally other than the difference in the interventions?  Yes   No   Not clear If no difference was found, was the sample size large enough to detect a difference if one existed?  Yes   No   Not clear If a difference was found, are you confident it was due to the intervention?  Yes   No   Not clear Are the findings consistent withfindings of other studies?  Yes   No   Not clear Are the findings credible?  Yes   No   Not clear Clinical Significance Is the target population clearly described?  Yes   No   Not clear Is the frequency, association, or treatment effect impressive enough for you to be confident that the finding would make a clinical difference if used as a basis for care?  Yes   No   Not clear Are the findings clinically significant?  Yes   No   Not clear Comments please answer the above. citation for the article appraisal is linked above. Thans data obtained with findings

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